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2012;7:e36910
Aetna typically requires BMI 30 with a comorbid condition (like hypertension or sleep apnea) or BMI 35 without comorbidities, plus documented diet and exercise failure

Yavas, O., Aytemir, K., & Celik, I

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Several liver enzymes use Cu for their activity: the ferroxidase ceruloplasmin (CP), an abundant Cu-binding protein secreted by hepatocytes into the blood ( FIGURE 1 (B) Expression of ATP7B, CP and CTR in liver cells
