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The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces

Graaf CD, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, et al

Catechins perform a dual action regarding ROS homeostasisthey act as potent antioxidants under normal conditions, and as prooxidants under pathological conditions, activating the pathways which signal cell death

To ensure efficacy, specific administration guidelines have been established

Martin D, Thaker J, Shreve M, Lamerato L, Budzynska K
