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10.3390/antiox11112247 112 PopracP.JomovaK.SimunkovaM.KollarV.RhodesC

doi: 10.3389/fphar.2020.00872 9 PittasKVrachatisDAAngelidisCTsoucalaSGiannopoulosGDeftereosS

L.ZirlikA.MacFarlaneL

In this model, the reduced anti-tumor immunity of sleep-deprived animals was also indexed by the reduced number of antigen-presenting cells (dendritic cells) in the lymph nodes, as well as by the decreased effector CD4 T-cell numbers and corresponding cytokine profile (decreased IFN-), resulting in lowered Th1 response of Th cells, i.e., the most effective immune response against tumors

Phosphorodiamidate morpholino oligonucleotides (PMOs) are another class of nucleic acid analogs with significant potential, which are characterized by a six-membered morpholine ring backbone