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Pathophysiology of skeletal muscle disturbances in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Karki P., Smith K., Johnson J., Aschner M., Lee E.Y

In cases of genetic ALS, mutations lead to motor neuron pathology via multiple mechanisms, such as oxidative stress with SOD1 and RNA processing with C9orf72

Although this study was exploratory in nature and aimed primarily to identify and validate potential mechanistic targets, the limited sample size underscores the need for caution in interpreting clinical diagnostic relevance

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