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Description
Vitamin B12 is found primarily in animal-source foods including meat, fish, dairy products, and eggs

The goal of the 3R Principle is to avoid animal experiments altogether (Replacement) and to limit the number of animals (Reduction) and their suffering (Refinement) in tests to an absolute minimum

Shrimp JH, Hu J, Dong M, Wang BS, MacDonald R, Jiang H, et al

It is better absorbed and retained by most tissues

That review also found moderate evidence that treatment with vitamin B12 does not improve dementia and that oral supplements are as effective as injections of vitamin B12
