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Elevated serum ALT levels are observed in acute hepatitis, and the ratio of AST to ALT is an important indicator of alcoholic hepatitis [30]
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However, successful clinical translation will require a deeper understanding of redox thresholds across cell types, subcellular compartments, and disease stages, as well as strategies to overcome compensatory antioxidant networks and systemic toxicity associated with non-specific redox modulation

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Two large population-based studies reported that the rate of paracetamol poisoning decreased with age from a peak in adolescence and early adulthood [60, 61]
