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2014;134(4):e1282

The authors established a link between Nrf2 signalling pathways and the regulation of spermatogenesis and sperm quality

Phytofurans Under increased oxygen tension, such as in highly oxygenated tissues like lung, brain, and kidneys, cyclic nonenzymatic metabolites possessing a substituted tetrahydrofuran ring (PhytoFs) are preferentially formed compared to phytoprostanes

In addition, complete FXN-knockout mice are embryonic lethal, and thus our best mouse models are those which are temporally conditional FXN deficient or those which exhibit tissue-specific FXN loss (Cosse et al., 2000)

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