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It has been indicated that prolonged administration of MSG (4 mg/g) significantly induces apoptosis in a time- dependent manner in the rats thymocyte cells via disturbing the fine balances between prooxidant-antioxidant system, with excessive production of ROS and resulting oxidative stress status [46]
doi: 10.1182/blood-2013-10-532200 3 VangapanduHVAlstonBMorseJAyresMLWierdaWGKeatingMJet al
Suzuki T, Takahashi J, Yamamoto M
Together, these observations strongly suggested that GSH regulated the subcellular Fe homeostasis via a GSNO mediated pathway
