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ACSL4 inhibitors have decreased ferroptosis in AD mice, but their poor target selectivity makes them unsuitable for human trials (Jia et al., 2023

Adeno-associated virus serotype 9 antibodies in patients screened for treatment with onasemnogene abeparvovec

The sensitivity of these cells to ferroptosis could be leveraged to modulate autoimmune responses (74)

Microbiota dysbiosis, such as changes in the structure, quantity, and variety of bacteria, increases the susceptibility of the host to infection by various pathogens, exacerbates gut and brain autoimmunity and inflammation, induces diverse methods of metabolic disorders, and fosters the progression of neurological diseases