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[PubMed: 2161554] 242

Both substances are linked to leukoencephalopathy

Additionally, significant enrichment was observed in pathways related to xenobiotic biodegradation (15.75%) and the metabolism of cofactors and vitamins (9.38%)

2.3 Demyelination and cellularity differences between C57BL/6J and C57BL/6NTac strains Sections were semi-quantitatively evaluated for decrease in LFB staining (indicative of demyelination) and for increased cellularity in the corpus callosum (indicative of reactive gliosis) (Supplementary Table 2)

Prebiotics selectively stimulate the growth of beneficial bacteria, thereby influencing metabolic pathways related to glucose homeostasis and neuroprotection