glutathione system mechanism Glutathione: The “Master” Antioxidant – Core Med Science Glutathione antioxidant system. a Schematics

The substrate undergoes a sulfur transfer reaction in the presence of pyridoxal-5-phosphate, forming L-homocysteine, which takes part in the methylation cycle

Inhibition of neuronal glutamine transporters resulted in decreased levels of Glu-Gln in the mPFC and manifested depressive-like behaviors [14], and a reduction of their expression was observed in CIS-induced depressive mice [18]

Hu H, Li Z, Zhu X et al (2014) Salidroside reduces cell mobility via NF-B and MAPK signaling in LPS-induced BV2 microglial cells

The Aging Problem Here's the part that matters practically

Durian pulp is rich in valuable bioactive compounds, including polyphenols, such as flavonoids (flavanones, flavonols, flavones, flavanols, and anthocyanins), phenolic acids (cinnamic acid and hydroxybenzoic acid), tannins, and other bioactive components like carotenoids and ascorbic acid [13]