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Description

Significance was determined by one-way repeated measures analysis of variance, and the HolmSidak method for multiple comparisons versus the control group, using SigmaPlot 10.0 software (Systat Software, San Jose, CA, USA)

The compound demonstrates exceptional target selectivity, with no inhibition of related methyltransferases (DNMT1, PRMT3, COMT) or NAD+ salvage enzymes (NAMPT, SIRT1) at concentrations up to 600 M

[Google Scholar] Schipper NG, Varum KM, Artursson P

Category 2: The enzyme modulators The second category of nootropics is comprised of those which interact with enzymes, usually in order to increase or decrease levels of an associated neurotransmitter