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In the shuttle, glutamate is converted to glutamine in astrocytes, and then exported to neuronal system A transporters, where it is converted to glutamate intracellularly by phosphate activated glutaminase (21)

Starting with smaller amounts (1 teaspoon) and gradually increasing allows the digestive system to adapt to the fiber content and helps identify individual tolerance levels

For chronic diseases, 50% of the dose indicated above will be used