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The ability to measure bioenergetics parameters in cells depends on sensitive measurement of dioxygen consumption before and after carefully defined addition of first an ATPase inhibitor (oligomycin) to define ATP production in the respiring cells, then an uncoupler [carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (FCCP)] to allow maximal respiration, then inhibitors (rotenone and antimycin A), as shown in Fig

Lack of effect of oral vitamin C on blood pressure, oxidative stress and endothelial function in Type II diabetes

Zhao, D., et al

Spondyloepimetaphyseal dysplasia with neurodegeneration associated with aifm1 mutation - a novel phenotype of the mitochondrial disease