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Each component has different properties, different mechanisms, and potentially different dose-response curves

Joung J

10.1016/j.jdiacomp.2018.01.015 9 BeatonM

Additionally, Chinese propolis extracts have been shown to lower blood pressure and improve myocardial function in hypertensive rats through mechanisms involving catecholamine synthesis inhibition, endothelium-dependent vasodilation, and vascular anti-inflammatory activity [176]

Bioinformatics analysis, including hierarchical cluster, gene ontology, pathway, and network, was performed using Blast2GO (Version 3.5.0), the online Kyoto Encyclopedia of Genes and Genomes (KEGG) database ( and the InAct molecular interaction database ( Differentially expressed proteins between the two groups were screened using fold change method (2 fold)