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It is necessary to integrate multi-omics data such as gut metagenomics, metatranscriptomics, and metabolomics, combined with machine learning, to map unique microbe-metabolic dysfunction landscapes for each patient, identifying key pathogens, defective beneficial bacteria, and dysregulated core metabolic pathways

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Drug-Drug Interactions: Erythromycin: Co-administration of orally administered azelastine (4 mg twice daily) with erythromycin (500 mg three times daily for 7 days) resulted in Cmax of 5.36 2.6 ng/mL and AUC of 49.7 24 ngh/mL for azelastine, whereas, administration of azelastine alone resulted in Cmax of 5.57 2.7 ng/mL and AUC of 48.4 24 ngh/mL for azelastine [see Drug Interactions (7.2)]

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