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Development of a first-in-class DNMT1/HDAC inhibitor with improved therapeutic potential and potentiated antitumor immunity

The drug was developed in the 1940s by Albert Hofmann [138], and thus, is one of the oldest nootropic drugs still in use

The optimal mRNA-LNP ssPalmE also shows prophylactic activity against lethal infections of Toxoplasma gondii when an antigen derived from this protozoa is coded in the mRNA

The exposure was taken from the maximum predicted value across all relevant generations on that day (1, 4, 8, and 12), which was recorded for both the upper and lower lung (Table 3