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The strong link between a higher BMI and sarcoidosis is consistent with the idea that adipose-related inflammation can exacerbate granulomatous disease

After 4 days, cells were induced to differentiate with high glucose (4.5 g/l) DMEM supplemented with 10% fetal bovine serum (FBS), 5 g/ml insulin, 1 M dexamethasone and 0.5 mM 3-isobutyl-1-methylxanthine (IBMX)

Following incubation at 56C for 30 min, IA-DTB (10 l 200 mM fresh stock in DMSO, final concentration: 20 mM) was added and samples were incubated 37 C for 1 hour with shaking

Also, the ELWL content showed the greatest decrease of 98% compared to the control

Shave excision: The lesion is shaved off, often used when histology is required