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This modification allows IGF-1 LR3 to remain free-floating in the bloodstream and exert more direct anabolic effects (Jones & Clemmons, Endocrine Reviews )

Construction was confirmed by PCR (Fig

This should be a control of the release of glutamate in the synaptic cleft from presynaptic terminals to stimulate post-synaptic neurons (i.e., the NMDA receptors) and re-uptake from the cleft by the excitatory amino acid transporters (EAAT) into astrocytes, and glutamate/glutamine cycle within astrocytes [59]

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Its classified as a pentadecapeptide and belongs to a group of synthetic peptides used for tissue regeneration and healing