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After completing the digestion step, gel-embedded tissue sections were placed in double-deionized water for 60 min for isotropic expansion
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The caspase3 protein expression level was significantly down-regulated in the high glucose + curcumin group relative to the high glucose group, while the Bcl2 expression was up-regulated

This is especially important for those on chemotherapy, immunosuppressants, or medications for diabetes and kidney conditions, as antioxidants and minerals can sometimes influence drug effectiveness
doi: 10.1523/JNEUROSCI.17-09-03064.1997
