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however, patients with severe neurological complications or critically low B12 status should be treated with i.m
Most others who Ive spoken with that had more severe acute reactions like nausea etc

A recent study on P-gp comparing gastro-intestinal tissue from Wistar rats and humans confirmed the translatability of experimental findings on discovered sex differences (Mai et al., 2021)

NF-kB can become chronically elevated because of its own amplifying loop
Similarly, with murine models, nose-only and whole-body inhalation chambers can be used to test antioxidant aerosol pre-treatment followed by air pollution exposure in a whole body gas or PM exposure chambers [100, 101]