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Up-regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-cell Proliferation and Transforms T-cells Towards a Tumor-tolerating Phenotype

doi: 10.1007/BF01086149

Use distraction and relaxation techniques to reduce anxiety if needed

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Although the detailed investigation report by Alnylam illustrated that the deaths of revusiran-treated patients were not correlated with the test drug, there are still strong concerns regarding STC-modified siRNA therapeutics