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16,18-20 If you think you injected too high, or you suspect a patient has SIRVA, educate the patient about what SIRVA is and tell them to see a doctor if pain in their shoulder increases or if they lose range of motion after 2 days that does not improve

Both come down to the concentration you want

No published research characterizes adverse events at sustained injectable doses above 5-10 mg/week in humans

This graphic from CDC below shows how MTHFR gene mutations of C677T variant transfer from parents to children and grandchildren in a family

This is the focus mostly because BPC-157 was originally derived from a protein that is found in the gut