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In terms of safety and tolerability of the compound, there were fewer adverse events per 100 patients across all experimental groups administered cagrilintide

For example, the lysosomal cysteine protease cathepsin B (CTSB) promotes autophagy-dependent ferroptosis via translocation from lysosome into nucleus to cause DNA damage signals and to activate stimulator of interferon response cGAMP interactor 1 (STING1, also known as STING or TMEM173)-dependent DNA sensor pathways (39) ( Figure 2 )

10.1080/01616412.2018.1564451 36 KowiaskiP.LietzauG.CzubaE.WakowM.SteligaA.MoryJ.et al

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