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To evaluate the impact of Syn constructs on chaperone-mediated refolding, denatured luciferase (40 nM) was incubated with DNAJB1 (1.0 M) and HSPA8 (2.0 M) in the presence of Syn constructs at a molar ratio of 1:2 (HSPA8:Syn)

Doses vary based on age, sex and weight, states Axe

Glycogen synthesis/phosphorolysis is regulated via phosphorylation of cognate enzymes, absent a requirement for gene activation or de novo protein synthesis

Ethical approval The study was conducted in accordance with the ethical principles that have their origin in the Declaration of Helsinki

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