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Skulska K, Kdzierska AE, Krzyowska M, Chodaczek G

Interestingly, in traumatic brain injury, GPx1 deficiency was associated with decreased mitochondrial bioenergetic capacity compared to wildtype mice, whereas transgenic GPx1 mice had no decrease in mitochondrial function [114] GPx1 deficiency also enhanced apoptosis and inflammation in a cold-induced brain injury model [115]

Pierce BCA protein assay kit was applied to measure the total protein concentration of cell lysates

doi: 10.1007/s00122-006-0275-5 134 MesekaS.MenkirA.BosseyB.MengeshaW

Oxidative stress caused by a variety of agents and drug-resistant tumor cell lines are two conditions associated with increased cell GSH levels, GCL activity, GCLC mRNA levels and GCLC gene transcription (Mulcahy et al., 1994a