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The CAG140 knock-in (KI) mouse model exhibits abnormal mHTT aggregates, striatal transcriptional deficits, and early-onset motor, cognitive and affective impairments

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Clin Cosmet Investig Dermatol 10:147153 Wheeler GL, Trotter EW, Dawes IW, Grant CM (2003) Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors

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Every cell contains NAD+ (Nicotinamide Adenine Dinucleotide) that plays a vital role in energy production, DNA repair, and cellular function