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RS and HL drafted and critically revised the manuscript

Conclusion This is the first MR analysis to investigate the causality of CSF and blood metabolites in NMOSD

CNF toxin binds to the tight junctions of colonic epithelial cells which internalize it by endocytosis and promotes cell proliferation by encouraging entry into the cell cycle and the G1/S transition for cell survival by inducing, in particular, the expression of the anti-apoptotic proteins Bcl-2 (B-cell lymphoma 2) and Bcl-xl (B-cell lymphoma-extra-large) [154]

HucTDrapalaAGawrysMKonopMBielinskaKZaorskaEet al

E., von Amsberg, G., Janning, M
