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Compared to WT NS3, NS3 S117D and NS3 S182D showed significant reductions in accumulation when transiently expressed in N

The SELECT trial (2023) further established semaglutides cardiovascular benefits, showing a 20% reduction in major adverse cardiovascular events in overweight adults with established heart disease even without diabetes

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A.ScheuermaierK.BelenkyM.et al (2023)
