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It has been found that estradiol benzoate, for example, causes a change in the expression of ECS components (CB 1 R, CB 2 R, FAAH) in the rat uterus, in an estrogen receptor-dependent way, indicating potential for hormonal regulation of the ECS in reproductive tissues (Maia et al., 2017)
Established protocols help clinicians decide on the appropriate initial dosing and then titer it to bring TSH within the standard reference range [3]
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