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[DOI] [PubMed] [Google Scholar] 136.Wei E, Lehner R, Vance DE

Preliminary findings indicate that TB-500 might enhance not only the viability, angiogenesis, and migration of HUVEC but could also elevate the expression of angiopoietin-2 (Ang2), TEK receptor tyrosine kinase 2 (tie2), vascular endothelial growth factor A (VEGFA), NOTCH1 intracellular domain (N1ICD), Notch receptor 3 (Notch3), NF-B, and phosphorylated (p)-p65 in these cells

Week 7-8+: Continue maintenance as needed
Carmel R, Tatsis B, Baril L
neurological involvement requires more frequent maintenance dosing
