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A blood test is used to diagnose vitamin B12 deficiency
This depends on how severe the deficiency is, any health conditions, and how well the therapy works
The cycling protocols commonly recommended are partly based on this theoretical concern, though actual tolerance development has not been documented
The intranasal forms of methylcobalamin, vitamin B12, should be administered at least 1 hour before or 1 hour after ingestion of hot food or liquids
