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doi: 10.1073/pnas.2508311122
Statins, which work by inhibiting the enzyme hydroxymethylglutaryl coenzyme A reductase, are the standard treatment for lowering high cholesterol levels
Heres my explanation to the paradox
Nuclear receptors PPAR [67] and estrogen receptor (ER) [68] can directly bind to NRF2 and suppress the NRF2 activity
[DOI] [PubMed] [Google Scholar] 8.Hwa V, Oh Y, Rosenfeld RG
