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The preclinical research suggests the receptor upregulation is time-dependent, so this is a real question

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In the past two decades, proteomics has been applied to study stress response to nutrient limitations, metabolism of various carbon and nitrogen sources, the lipid droplet hub of carbon storage, protein post-translational modifications and signaling pathways, as well as oleochemical biosynthesis, thereby advancing our understanding of the oleaginous phenotype

10.1016/j.vetimm.2003.12.010

Defensins are synthesized in vivo as inactive precursor proteins
