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Reduced absorption may necessitate higher doses, increasing the risk of adverse effects, while reduced mucociliary clearance may put patients at greater risk of acquiring respiratory infections or pneumonia

Loss of glutathione in NE neurons may disrupt the overall oxidative balance and cellular health, and a reduction in surface EAAT3 following AMPH administration could make cells more vulnerable to other perturbations

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10.1016/j.cellsig.2011.05.004 85 HeshmatiJ.MoiniA.SepidarkishM.MorvaridzadehM.SalehiM.PalmowskiA.et al (2021)

Distinct origins, gene expression and function of microglia and monocyte-derived macrophages in CNS myelin injury and regeneration