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In the nineties, Sikiric licensed the compound to a Croatian company called Pliva, which sought a treatment for ulcerative colitis

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Last reviewed: July 3, 2026 Last updated: July 3, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Arctigenin activates the Tolllike receptor signaling pathway in macrophages, enhancing their phagocytic and cytotoxic capabilities [221]

Although I'm based in Durham, I'm happy to travel to Raleigh and Chapel Hill at no additional fee