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These studies typically enroll a small cohort of 20 to 100 healthy volunteers, though patients with the target disease may be used for highly toxic medications like chemotherapeutics

Synthesis of the acid-labile subunit of the growth-hormone-dependent insulin-like-growth-factor-binding protein complex by rat hepatocytes in culture

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-Methyltryptophan (-MT), a pharmacological inhibitor of SLC6A14, can inhibit the proliferation of cancer cells in vitro and tumor growth in vivo ( After catalysis by GLS in cells, glutamine is converted into glutamate