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The UPR-mediated activation of autophagy has been extensively validated across various tumor models

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Most importantly, the immune dysregulation from increased permeability has been shown to perpetuate immune overzealousness and loss of ability to regulate self and nonself tolerance, leading to autoimmunity

Mutations in both HGF and MET genes are also linked to non-syndromic hearing impairment (NSHI), which is a partial or total loss of hearing that is not associated with other signs and symptoms

Lactoferrin Protects Gut Mucosal Integrity During Endotoxemia Induced by Lipopolysaccharide in Mice