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Several factors can affect how long the B12 shot lasts and how your body responds: Your B12 levels : The more deficient you are, the more dramatic and long-lasting the effects may be

[1] Always inspect the solution in good light before withdrawing a dose: it should appear clear and free of particles or haze

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Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial