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Immunohistochemical analysis, while providing valuable spatial protein expression data, revealed that nicorandil blunted the CCI-induced elevation of MAPK-ERK1/2 phosphorylation and TRPV1 protein levels in DRG neurons

The accumulation of H2O2 and ONOO- can contribute to oxidative and nitrosative stress, potentially leading to cellular damage and immune dysfunction ( Superoxide anions (O2) are primary ROS generated during cellular respiration and various metabolic processes

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J Biol Chem 283:2026820276 Dixon DP, Skipsey M, Edwards R (2010) Roles for glutathione transferases in plant secondary metabolism

Schubert D, Dargusch R, Raitano J, Chan SW