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145,146,147 DNA ligation The pathological DSBs are primarily repaired by the NHEJ, a process involves synapsis, end-processing and ligation
Finkley M., Appa Y., Bhandarkar S
These effects could potentially be beneficial in treating various neurological conditions, though clinical evidence remains extremely limited
For example, some studies have found that the secondary mutations of D1228N/V and Y1230C in the MET kinase domain are the main mechanisms for acquired resistance to crizotinib in METex14 patients receiving c-MET inhibitor treatment [149, 150]
Does AOD 9604 Work in Conjunction With Other Therapies
