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Feeling lethargic for no reason

Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction

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The negative effect may be attributed to the fact that VEGF also has the potential to stimulate the expression of matrix metalloproteinases (MMPs) and inhibit the expression of tissue inhibitors of metalloproteinases (TIMPs) in endothelial cells and fibroblasts (Pufe et al., 2005
