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The results indicate that VK2 enhances bone mass and cartilage thickness in OA rats, alleviates pain, and lowers the OARSI score

Especially, benzylidene-2-thiohydantoins and 5-benzylidene(thio)barbiturates showed greater inhibitory potency (Figure 7)

PMID: 34512198

Excessive shedding from vitamin A toxicity often begins 2-3 months after initiating high-dose supplementation, as the hair growth cycle requires time to manifest disruptions

Invasive Ther
