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Sixty-eight male C57BL/6 mice were fed either a standard or AGE-rich diet, then treated for 35 days and mated
Administration of a single ethosuximide dose of 500 mg with valproate (800 to 1,600 mg/day) to healthy volunteers (n=6) was accompanied by a 25% increase in elimination half-life of ethosuximide and a 15% decrease in its total clearance as compared to ethosuximide alone
