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Currently, dexrazoxane is the only FDA-approved option for preventing cardiotoxicity caused by anthracycline chemotherapy drugs

Sun T, Liu B, Li Y, Wu J, Cao Y, Yang S, et al
Fighting against skin aging: the way from bench to bedside
[PubMed 8427280] 1635

Upon release, ADP binds to P2Y1 and P2Y12 receptors, after which P2Y1 activation stimulates phospholipase C, leading to platelet shape changes and the initiation of aggregation [36], [37]