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Choffour P

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Song H., Konan L

Int J Mol Sci 20(22):5534
576 Tetrahydroxy stilbene glycoside (TSG) enhances the activation of Keap1/Nrf2/ARE and GSH/GPX4 signaling pathways, reduces ferroptosis by regulating the levels of ferroptosis-related proteins and enzymes, and thus inhibits the production and deposition of A in the brain of APP/PS1 mice, 577 suggesting that TSG may be a promising therapeutic agent for AD by targeting ferroptosis