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It has been used: As part of the treatment for cyanide poisoning To dye tissues during surgery to determine tumors To relieve pain caused by oral mucositis To identify orthopedic injury to joint capsules To treat malaria before modern treatments were developed To treat encephalopathy, or confusion caused by chemotherapy Exploring other uses for methylene blue Earlier in my career, while working in emergency medicine, I read two papers that discussed using methylene blue as part of photodynamic therapy for lichen planus, a type of precancerous lesion in the mouth

Rapid modifications of somatostatin neuron activity in the periventricular nucleus after acute stress

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When a patient comes to the hospital with an acetaminophen overdose, standard of care is to use intravenous NAC to protect the liver and help the body excrete accumulated toxins