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Answer: Semaglutide works by activating GLP-1 receptors to slow gastric emptying, increase fullness after meals, and reduce hunger and food cravings, so most people eat less without the constant fight against appetite

They also had reduced kidney function, indicated by increased plasma urea and increased renal tubular IL-6 expression

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They also provide an example analogous to the GST/JNK association and imply a broad ranging role for thiol:disulfide balance in the regulation of cellular functions and proliferation
Liu W, Chakraborty B, Safi R, Kazmin D, Chang CY, McDonnell DP
