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A glutathione s-transferase regulated by light and hormones participates in the modulation of arabidopsis seedling development

Only male mice were included in this study because of limited availability of aged mice

J Am Med Assoc 149:13851389 Patlolla AK, Barnes C, Yedjou C, Velma V, Tchounwou PB (2009) Oxidative stress, DNA damage, and antioxidant enzyme activity induced by hexavalent chromium in Sprague-Dawley rats

Combined with advancing age, poor lifestyle choices or environmental stressors, all of which reduce glutathione even further, poor health outcomes are likely

Animal experiments and clinical observations complement each other, jointly establishing the empirical foundation for the E-P-OS network framework and pointing the way for subsequent mechanism exploration