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In addition, gene therapy can enhance cellular antioxidant capacity by upregulating the expression of antioxidant enzymes, thus reducing ROS accumulation

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Long-term noise exposure can lead to damage of peripheral auditory system, including the structure of cochlea hair cells, cilia, supporting cells, and tectorial membrane (Wang et al., 2002), hitting the external layer of hair cells the most, and the Cortis organ and spiral ganglion may also undergo degenerative changes (Kurabi et al., 2017)

Dubos et al., 2010)

The total duration (minutes) of the recording period on three nights was assessed